January 25, 2010
U.S. doctors prescribing more psychiatric medications
Psychiatrists in the United States prescribed more psychotropic drugs to their patients in 2006 than they did a decade ago, according to an analysis by researchers at the Johns Hopkins Bloomberg School of Public Health and Columbia University.
The researchers also found that individual patients were prescribed medications in greater combination to treat their mental illnesses than in previous years. The study is published in the January edition of the journal Archives of General Psychiatry.
“Our analysis shows that there has been a recent and significant increase in the number of medications prescribed by psychiatrists in the U.S.,” said Ramin Mojtabai, lead author of the study and an associate professor in the Bloomberg School’s Department of Mental Health. “While some [combinations] of medications are supported by clinical trials, many are of unproven efficacy. These trends put patients at increased risk for potentially harmful drug interactions while the gains from better outcomes are uncertain.”
For the study, the researchers reviewed data from the National Ambulatory Medical Care Surveys. The cross-sectional study was a nationally representative sample of more than 13,000 office-based psychiatry visits from 1996 to 2006. In addition to finding a general increase in the number of medications prescribed, the study determined that the number of office visits with two or more medications prescribed increased from 42.6 percent in 1996–1997 to 59.8 percent in 2005–2006; visits in which patients received three or more medication prescriptions increased from 16.9 percent to 33.2 percent. The median number of medications prescribed per patient also increased, from one to two, over the survey period.
“A wide and ever-growing gap exists between the simple medication regimens that dominate clinical research trials and the complex regimens that increasingly characterize community psychiatric practice,” said Mark Olfson, co-author of the study and a professor of clinical psychiatry at Columbia University Medical Center.